Managing Hyperkalaemia: Getting Patients to Optimal RAASi Therapy
Originally delivered live, this roundtable programme brings together Prof James Burton (University of Leicester, Leicester, UK), Dr Clara Bonanad (University Clinical Hospital of Valencia, Valencia, ES), Dr Aaron Wong (Princess of Wales Hospital, Bridgend, Wales, UK) and Dr Csaba Kovesdy (University of Tennessee, Knoxville, US) to explore practical, evidence-based approaches to managing hyperkalaemia in clinical settings. The discussion focuses on real-world trends in the use of RAAS inhibitors (RAASi) and the challenges of maintaining guideline-directed medical therapy (GDMT) in the presence of hyperkalaemia.
This programme focuses on critical topics such as the clinical consequences of RAASi down-titration or discontinuation, the latest data on the prevalence and impact of hyperkalaemia in heart failure and related conditions and effective approaches to managing hyperkalaemia that support ongoing RAASi therapy.
Learning Objectives
- Interpret real-world trends in RAASi management and the impact of hyperkalaemia on GDMT
- Assess the effects of RAASi down-titration and discontinuation on patient outcomes
- Analyse real-world hyperkalaemia management evidence
- Apply RWE evidence to develop an expert-guided strategy for managing hyperkalaemia effectively to optimise RAASi therapy
Target Audience
- Nephrologists
- Cardiologists
- Healthcare Practitioners
- Global reach
More from this programme
Part 1
Key Take Home Messages
This video features Prof James Burton sharing key take-home messages and highlighting the core insights that are covered in the programme. It offers a concise overview of the most relevant themes and takeaways.
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Part 2
Real-world Practice in RAASi Optimisation
In this session, Prof James Burton together with Dr Clara Bonanad, Dr Aaron Wong and Dr Csaba Kovesdy, explore real-world RAASi management, treatment barriers, guideline insights, and the impact of therapy discontinuation on patient outcomes.
Part 3
Evidence Based Strategies for Hyperkalaemia Management & RAASi Maintenance
Dr Clara Bonanad presents key data on potassium binders, including REALIZE-K and ZORA studies, followed by panel discussion on real-world application and optimising RAASi and MRA therapy.
Part 4
Expert Consensus & Case Study Example
In this segment, Prof James Burton and Dr Aaron Wong give a brief re-cap on the case studies and pre-event poll results followed by faculty discussion on optimal management strategies. Topics include initial hyperkalaemia management, GDMT up-titration, monitoring, and working together as a multidisciplinary team to optimise patient outcomes.
Part 5
Audience Q&A
In this closing segment Prof James Burton highlights key take-home messages from the programme and reviews final poll results, reinforcing clinical insights and practical strategies discussed throughout the sessions.
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Faculty Biographies
James Burton
Professor of Renal Medicine
Prof James Burton is Honorary Consultant Nephrologist and Professor of Renal Medicine and Associate Dean for Clinical Research at the University of Leicester, Leicester, UK. His principal research interests are the mechanisms underlying uraemic cardiovascular disease modification of cardiovascular risk in patients with end-stage renal disease and the identification and application of novel biomarkers.
In addition Prof Burton is involved in the development and running of clinical trials; he is Chief Investigator for the NIHR funded NightLife trial investigating the impact of nocturnal dialysis on patient outcomes as well as the Kidney Research UK funded CONFIRM study exploring the utility of a novel cardiac magnetic resonance imaging (MRI) techniques in haemodialysis patients. Prof Burton is the independent Chair of two multi-centre NIHR Trial Steering Committees and sits on a number of others.
He is the current Chair of the UK Kidney Association Clinical…
Clara Bonanad Lozano
Dr Clara Bonanad Lozano is a cardiologist at the University Clinical Hospital of Valencia, ES and president of the Association of Geriatric Cardiology of the Spanish Society of Cardiology. Her clinical interests are Myocardial Infarction, Echocardiography, Pacemakers, Cardiac Imaging, Diabetes, Cardiovascular, and Heart Failure.
Aaron Wong
Consultant Cardiologist
Dr Aaron Wong is consultant cardiologist and general physician at the Princess of Wales Hospital, Bridgend, Wales, UK and is also an honorary lecturer at the University of Cardiff, UK.
His research interests include heart failure and cardiometabolic disease.
Csaba Kovesdy
Professor of Medicine in Nephrology
Prof Csaba P Kovesdy, is Professor of Medicine in Nephrology, Director of the Clinical Outcomes and Clinical Trials Program, and Medical Director of the Office of Clinical Research at the University of Tennessee Health Science Center, and Chief of Nephrology at the Memphis VA Medical Center in Memphis, Tennessee, US.
Prof Kovesdy’s principal research interests are centered on uncovering causes of morbidity and mortality with a focus on nutritional and metabolic abnormalities in patients with all stages of chronic kidney disease, with active involvement in observational, interventional, and translational research studies. Dr Kovesdy has published his research in over 550 peer-reviewed articles, as well as numerous abstracts and book chapters. He has served as the Treasurer of the International Society of Renal Nutrition and Metabolism during 2014-2018 and is currently an at-large member of the Executive Committee. Dr Kovesdy co-chairs the TNT Renal Program and…